Rationale:

Recurrent cystitis is repeated inflammation in the bladder usually caused by bacterial infection. It is common in adult females and often results in lower quality of life. In some people, bacteria remain in the bladder after treatment. A thin layer of bacteria can attach to the inside of the bladder and live as a community. The reasons why some people develop these communities is not completely known, but genetic differences in immunity may explain this increased risk. In addition, other bacteria and viruses live on our body surfaces without harming us and can prevent harmful bacteria from causing infection. This study will investigate these bacterial communities, genetic differences, and the presence of bacteria and viruses in urine.

Eligibility: 

• Female
• 18 years of age or older